Target name

P34976: Type-1 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P34976
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID ocu:100009164
DIP ID
STRING ID 9986.ENSOCUP00000024805
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 100009164
BindingDB P34976

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.929 0.003 0.991 0.000 0.960 0.000 0.960 0.000 0.999 0.003 0.920 0.000 Download
Estate fingerprints 0.950 0.000 0.868 0.006 0.909 0.003 0.911 0.003 0.980 0.000 0.820 0.005 Download
MACCS fingerprints 0.936 0.005 0.948 0.005 0.942 0.004 0.942 0.004 0.990 0.000 0.886 0.005 Download
Daylight fingerprints 0.890 0.000 0.950 0.005 0.920 0.000 0.920 0.000 0.970 0.000 0.844 0.005 Download
ECFP2 fingerprints 0.990 0.000 0.990 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.985 0.005 Download
ECFP4 fingerprints 0.990 0.000 0.990 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.989 0.003 Download
ECFP6 fingerprints 0.980 0.000 1.000 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.978 0.004 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn