Target name

P35218: Carbonic anhydrase 5A, mitochondrial


  Protein function

Reversible hydration of carbon dioxide. Low activity.

  Database links

Uniprot primary ID P35218
PDB ID
DrugBank ID DB01194 DB00909
BioGrid ID 107218
GuidetoPHARMACOLOGY ID
PharmGKB ID PA25992
KEGG ID hsa:763
DIP ID
STRING ID 9606.ENSP00000309649
IntAct ID
DMDM 461680
BRENDA 4.2.1.1
Reactome R-HSA-1475029
SignaLink
BioCyc
Entrez Gene (Gene ID) 763
BindingDB P35218

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.934 0.008 0.902 0.007 0.918 0.006 0.918 0.006 0.964 0.005 0.837 0.013 Download
Estate fingerprints 0.881 0.003 0.897 0.007 0.889 0.003 0.889 0.003 0.952 0.004 0.779 0.007 Download
MACCS fingerprints 0.809 0.003 0.869 0.005 0.839 0.003 0.833 0.007 0.940 0.000 0.677 0.007 Download
Daylight fingerprints 0.709 0.003 0.809 0.004 0.759 0.003 0.742 0.004 0.819 0.003 0.511 0.006 Download
ECFP2 fingerprints 0.944 0.008 0.894 0.007 0.919 0.006 0.921 0.003 0.980 0.000 0.842 0.008 Download
ECFP4 fingerprints 0.977 0.005 0.905 0.005 0.941 0.003 0.941 0.003 0.980 0.000 0.882 0.004 Download
ECFP6 fingerprints 0.970 0.007 0.924 0.003 0.947 0.005 0.947 0.005 0.982 0.004 0.893 0.009 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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