Details-Calcnet-TargetNet

Target name

P35236: Tyrosine-protein phosphatase non-receptor type 7

Protein function

Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.

Database links

Uniprot primary ID	P35236
PDB ID	2GPH 2QDP 2HVL 2A3K 3O4T 3O4U 2QDC 3O4S 3D44 2QDM 1ZC0 2GP0 3D42
DrugBank ID
BioGrid ID	111743
GuidetoPHARMACOLOGY ID
PharmGKB ID	PA34003
KEGG ID
DIP ID	DIP-29118N
STRING ID	9606.ENSP00000309116
IntAct ID	P35236
DMDM	20141721
BRENDA	3.1.3.48
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID)	5778
BindingDB	P35236

Model Performance Metrics

Fingerprint type	Sensitivity	SEN_std	Specificity	SPE_std	Accuracy	ACC_std	F1-score	F1-score_std	AUC	AUC_std	MCC	MCC_std	Download model
FP2 fingerprints	0.712	0.008	0.916	0.005	0.814	0.005	0.793	0.005	0.889	0.003	0.647	0.009	Download
Estate fingerprints	0.831	0.007	0.803	0.006	0.817	0.005	0.818	0.004	0.883	0.005	0.632	0.010	Download
MACCS fingerprints	0.823	0.008	0.831	0.007	0.827	0.007	0.827	0.007	0.880	0.000	0.652	0.009	Download
Daylight fingerprints	0.731	0.006	0.801	0.011	0.766	0.005	0.757	0.005	0.791	0.003	0.533	0.014	Download
ECFP2 fingerprints	0.894	0.005	0.864	0.007	0.879	0.006	0.883	0.005	0.946	0.005	0.762	0.010	Download
ECFP4 fingerprints	0.844	0.007	0.914	0.006	0.879	0.006	0.876	0.007	0.950	0.000	0.764	0.012	Download
ECFP6 fingerprints	0.790	0.012	0.930	0.003	0.860	0.007	0.850	0.007	0.942	0.004	0.731	0.014	Download

Download datasets

Positive dataset

Negative dataset