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E-mail: biomed@csu.edu.cn
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Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
| Uniprot primary ID | P37058 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 109526 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | PA29480 |
| KEGG ID | hsa:3293 |
| DIP ID | |
| STRING ID | 9606.ENSP00000364412 |
| IntAct ID | P37058 |
| DMDM | 1169300 |
| BRENDA | 1.1.1.51 1.1.1.64 |
| Reactome | R-HSA-193048 R-HSA-75876 |
| SignaLink | |
| BioCyc | MetaCyc:HS05461-MONOMER |
| Entrez Gene (Gene ID) | 3293 |
| BindingDB | P37058 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.928 | 0.008 | 0.932 | 0.003 | 0.930 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.857 | 0.008 | Download |
| Estate fingerprints | 0.839 | 0.017 | 0.905 | 0.009 | 0.872 | 0.010 | 0.867 | 0.012 | 0.950 | 0.000 | 0.743 | 0.020 | Download |
| MACCS fingerprints | 0.894 | 0.005 | 0.914 | 0.005 | 0.904 | 0.005 | 0.904 | 0.005 | 0.953 | 0.005 | 0.808 | 0.008 | Download |
| Daylight fingerprints | 0.934 | 0.011 | 0.868 | 0.005 | 0.901 | 0.007 | 0.905 | 0.005 | 0.924 | 0.005 | 0.806 | 0.012 | Download |
| ECFP2 fingerprints | 0.979 | 0.009 | 0.923 | 0.006 | 0.951 | 0.006 | 0.951 | 0.006 | 0.990 | 0.000 | 0.901 | 0.010 | Download |
| ECFP4 fingerprints | 0.986 | 0.005 | 0.924 | 0.007 | 0.955 | 0.005 | 0.955 | 0.005 | 1.000 | 0.000 | 0.907 | 0.009 | Download |
| ECFP6 fingerprints | 0.977 | 0.005 | 0.943 | 0.003 | 0.960 | 0.000 | 0.960 | 0.000 | 1.000 | 0.000 | 0.919 | 0.003 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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