Target name

P37288: Vasopressin V1a receptor


  Protein function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.

  Database links

Uniprot primary ID P37288
PDB ID 1YTV
DrugBank ID DB02638 DB00093 DB00872 DB06212 DB00067 DB00035
BioGrid ID 107033
GuidetoPHARMACOLOGY ID 366
PharmGKB ID PA25187
KEGG ID hsa:552
DIP ID
STRING ID 9606.ENSP00000299178
IntAct ID P37288
DMDM 586197
BRENDA
Reactome R-HSA-388479 R-HSA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 552
BindingDB P37288

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.856 0.005 0.882 0.004 0.869 0.003 0.869 0.003 0.940 0.000 0.739 0.007 Download
Estate fingerprints 0.845 0.008 0.743 0.005 0.794 0.005 0.804 0.005 0.853 0.005 0.594 0.008 Download
MACCS fingerprints 0.827 0.007 0.719 0.006 0.773 0.005 0.783 0.005 0.884 0.005 0.549 0.007 Download
Daylight fingerprints 0.785 0.005 0.785 0.005 0.785 0.005 0.785 0.005 0.842 0.004 0.570 0.007 Download
ECFP2 fingerprints 0.882 0.004 0.938 0.005 0.910 0.000 0.908 0.004 0.970 0.000 0.820 0.005 Download
ECFP4 fingerprints 0.909 0.003 0.989 0.005 0.949 0.003 0.948 0.004 0.980 0.000 0.898 0.004 Download
ECFP6 fingerprints 0.890 0.005 0.990 0.000 0.940 0.000 0.938 0.004 0.980 0.000 0.884 0.005 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn