Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
Uniprot primary ID | P37288 |
PDB ID | 1YTV |
DrugBank ID | DB02638 DB00093 DB00872 DB06212 DB00067 DB00035 |
BioGrid ID | 107033 |
GuidetoPHARMACOLOGY ID | 366 |
PharmGKB ID | PA25187 |
KEGG ID | hsa:552 |
DIP ID | |
STRING ID | 9606.ENSP00000299178 |
IntAct ID | P37288 |
DMDM | 586197 |
BRENDA | |
Reactome | R-HSA-388479 R-HSA-416476 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 552 |
BindingDB | P37288 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.856 | 0.005 | 0.882 | 0.004 | 0.869 | 0.003 | 0.869 | 0.003 | 0.940 | 0.000 | 0.739 | 0.007 | Download |
Estate fingerprints | 0.845 | 0.008 | 0.743 | 0.005 | 0.794 | 0.005 | 0.804 | 0.005 | 0.853 | 0.005 | 0.594 | 0.008 | Download |
MACCS fingerprints | 0.827 | 0.007 | 0.719 | 0.006 | 0.773 | 0.005 | 0.783 | 0.005 | 0.884 | 0.005 | 0.549 | 0.007 | Download |
Daylight fingerprints | 0.785 | 0.005 | 0.785 | 0.005 | 0.785 | 0.005 | 0.785 | 0.005 | 0.842 | 0.004 | 0.570 | 0.007 | Download |
ECFP2 fingerprints | 0.882 | 0.004 | 0.938 | 0.005 | 0.910 | 0.000 | 0.908 | 0.004 | 0.970 | 0.000 | 0.820 | 0.005 | Download |
ECFP4 fingerprints | 0.909 | 0.003 | 0.989 | 0.005 | 0.949 | 0.003 | 0.948 | 0.004 | 0.980 | 0.000 | 0.898 | 0.004 | Download |
ECFP6 fingerprints | 0.890 | 0.005 | 0.990 | 0.000 | 0.940 | 0.000 | 0.938 | 0.004 | 0.980 | 0.000 | 0.884 | 0.005 | Download |
Positive dataset | Negative dataset |
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