TargetNet
  Target name

P42892: Endothelin-converting enzyme 1

  Protein function

Converts big endothelin-1 to endothelin-1.

  Database links
Uniprot primary ID P42892
PDB ID 3DWB
DrugBank ID
BioGrid ID 108218
GuidetoPHARMACOLOGY ID 1615
PharmGKB ID PA27594
KEGG ID hsa:1889
DIP ID
STRING ID 9606.ENSP00000364028
IntAct ID P42892
DMDM 1706563
BRENDA 3.4.24.71
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 1889
BindingDB P42892
  Model Performance Metrics
Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.836 0.011 0.950 0.003 0.893 0.007 0.887 0.005 0.965 0.005 0.791 0.010 Download
Estate fingerprints 0.844 0.005 0.882 0.007 0.863 0.005 0.857 0.005 0.940 0.000 0.725 0.011 Download
MACCS fingerprints 0.820 0.005 0.892 0.005 0.856 0.005 0.851 0.003 0.930 0.000 0.713 0.007 Download
Daylight fingerprints 0.717 0.005 0.959 0.007 0.838 0.004 0.814 0.005 0.929 0.003 0.690 0.005 Download
ECFP2 fingerprints 0.953 0.007 0.957 0.000 0.955 0.005 0.955 0.005 0.990 0.000 0.912 0.006 Download
ECFP4 fingerprints 0.966 0.005 0.980 0.000 0.973 0.005 0.973 0.005 0.998 0.004 0.947 0.005 Download
ECFP6 fingerprints 0.939 0.006 0.983 0.005 0.961 0.003 0.961 0.003 0.996 0.005 0.923 0.005 Download
  Download datasets
Positive dataset Negative dataset

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 E-mail: biomed@csu.edu.cn