Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
| Uniprot primary ID | P43119 |
| PDB ID | |
| DrugBank ID | DB01160 DB01088 DB01240 DB00374 |
| BioGrid ID | 111711 |
| GuidetoPHARMACOLOGY ID | 345 |
| PharmGKB ID | PA291 |
| KEGG ID | hsa:5739 |
| DIP ID | |
| STRING ID | 9606.ENSP00000291294 |
| IntAct ID | |
| DMDM | 1172500 |
| BRENDA | |
| Reactome | R-HSA-391908 R-HSA-418555 R-HSA-392851 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 5739 |
| BindingDB | P43119 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.871 | 0.006 | 0.907 | 0.005 | 0.889 | 0.003 | 0.885 | 0.007 | 0.949 | 0.003 | 0.775 | 0.011 | Download |
| Estate fingerprints | 0.848 | 0.006 | 0.824 | 0.008 | 0.836 | 0.005 | 0.837 | 0.005 | 0.899 | 0.003 | 0.670 | 0.008 | Download |
| MACCS fingerprints | 0.818 | 0.008 | 0.830 | 0.005 | 0.824 | 0.005 | 0.823 | 0.005 | 0.909 | 0.003 | 0.646 | 0.010 | Download |
| Daylight fingerprints | 0.684 | 0.022 | 0.952 | 0.005 | 0.818 | 0.011 | 0.791 | 0.018 | 0.937 | 0.005 | 0.663 | 0.022 | Download |
| ECFP2 fingerprints | 0.924 | 0.010 | 0.948 | 0.004 | 0.936 | 0.005 | 0.936 | 0.005 | 0.980 | 0.000 | 0.871 | 0.007 | Download |
| ECFP4 fingerprints | 0.920 | 0.012 | 0.980 | 0.004 | 0.950 | 0.005 | 0.949 | 0.006 | 0.988 | 0.004 | 0.902 | 0.009 | Download |
| ECFP6 fingerprints | 0.870 | 0.012 | 0.996 | 0.000 | 0.933 | 0.007 | 0.930 | 0.007 | 0.979 | 0.003 | 0.876 | 0.013 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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