Target name

P46663: B1 bradykinin receptor


  Protein function

This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

  Database links

Uniprot primary ID P46663
PDB ID
DrugBank ID
BioGrid ID 107092
GuidetoPHARMACOLOGY ID 41
PharmGKB ID PA79
KEGG ID hsa:623
DIP ID
STRING ID 9606.ENSP00000216629
IntAct ID P46663
DMDM 85681914
BRENDA
Reactome R-HSA-418594 R-HSA-375276 R-HSA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 623
BindingDB P46663

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.888 0.004 0.932 0.000 0.910 0.000 0.910 0.000 0.970 0.000 0.823 0.005 Download
Estate fingerprints 0.910 0.000 0.790 0.003 0.850 0.000 0.859 0.003 0.911 0.003 0.703 0.005 Download
MACCS fingerprints 0.787 0.005 0.871 0.004 0.829 0.003 0.821 0.003 0.920 0.000 0.660 0.005 Download
Daylight fingerprints 0.839 0.003 0.883 0.005 0.861 0.003 0.861 0.003 0.930 0.000 0.727 0.007 Download
ECFP2 fingerprints 0.968 0.004 0.952 0.004 0.960 0.000 0.960 0.000 0.990 0.000 0.922 0.004 Download
ECFP4 fingerprints 0.967 0.005 0.991 0.005 0.979 0.003 0.979 0.003 1.000 0.000 0.952 0.004 Download
ECFP6 fingerprints 0.943 0.005 0.997 0.000 0.970 0.000 0.970 0.000 0.997 0.005 0.943 0.005 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn