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E-mail: biomed@csu.edu.cn
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Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity).
| Uniprot primary ID | P56658 |
| PDB ID | 1WXY 1WXZ 1NDV 1NDY 1NDZ 1NDW 2E1W 1UML 1V7A 1QXL 1VFL 1KRM 1O5R 1W1I 2BGN 2Z7G 1V79 |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | bta:280712 |
| DIP ID | |
| STRING ID | 9913.ENSBTAP00000006947 |
| IntAct ID | P56658 |
| DMDM | |
| BRENDA | 3.5.4.4 |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 280712 |
| BindingDB | P56658 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.746 | 0.016 | 1.000 | 0.000 | 0.873 | 0.008 | 0.854 | 0.011 | 0.999 | 0.003 | 0.770 | 0.013 | Download |
| Estate fingerprints | 0.939 | 0.003 | 0.961 | 0.005 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.901 | 0.003 | Download |
| MACCS fingerprints | 0.922 | 0.004 | 0.978 | 0.004 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.903 | 0.005 | Download |
| Daylight fingerprints | 0.818 | 0.008 | 0.994 | 0.000 | 0.906 | 0.005 | 0.898 | 0.008 | 0.983 | 0.005 | 0.826 | 0.008 | Download |
| ECFP2 fingerprints | 0.970 | 0.000 | 0.990 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.970 | 0.000 | Download |
| ECFP4 fingerprints | 0.970 | 0.005 | 0.992 | 0.000 | 0.981 | 0.003 | 0.980 | 0.000 | 1.000 | 0.000 | 0.965 | 0.005 | Download |
| ECFP6 fingerprints | 0.951 | 0.006 | 0.993 | 0.000 | 0.972 | 0.004 | 0.970 | 0.000 | 1.000 | 0.000 | 0.949 | 0.003 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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