Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
| Uniprot primary ID | Q01959 |
| PDB ID | |
| DrugBank ID | DB01161 DB01146 DB06148 DB08824 DB01149 DB01104 DB00370 |
| BioGrid ID | 112422 |
| GuidetoPHARMACOLOGY ID | 927 |
| PharmGKB ID | PA311 |
| KEGG ID | hsa:6531 |
| DIP ID | DIP-41827N |
| STRING ID | 9606.ENSP00000270349 |
| IntAct ID | Q01959 |
| DMDM | 266667 |
| BRENDA | |
| Reactome | R-HSA-442660 R-HSA-379401 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 6531 |
| BindingDB | Q01959 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.890 | 0.000 | 0.810 | 0.000 | 0.850 | 0.000 | 0.854 | 0.005 | 0.910 | 0.000 | 0.699 | 0.003 | Download |
| Estate fingerprints | 0.860 | 0.000 | 0.780 | 0.005 | 0.820 | 0.000 | 0.830 | 0.000 | 0.900 | 0.000 | 0.646 | 0.005 | Download |
| MACCS fingerprints | 0.861 | 0.003 | 0.799 | 0.003 | 0.830 | 0.000 | 0.833 | 0.005 | 0.890 | 0.000 | 0.660 | 0.000 | Download |
| Daylight fingerprints | 0.720 | 0.000 | 0.780 | 0.003 | 0.750 | 0.000 | 0.743 | 0.005 | 0.800 | 0.000 | 0.510 | 0.000 | Download |
| ECFP2 fingerprints | 0.941 | 0.003 | 0.921 | 0.000 | 0.931 | 0.003 | 0.933 | 0.005 | 0.970 | 0.000 | 0.870 | 0.000 | Download |
| ECFP4 fingerprints | 0.930 | 0.000 | 0.950 | 0.000 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.887 | 0.005 | Download |
| ECFP6 fingerprints | 0.923 | 0.005 | 0.939 | 0.000 | 0.931 | 0.003 | 0.930 | 0.000 | 0.970 | 0.000 | 0.867 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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