Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
| Uniprot primary ID | Q13946 |
| PDB ID | 1ZKL 3G3N 4PM0 4Y2B |
| DrugBank ID | DB00651 DB00920 DB00201 |
| BioGrid ID | 111176 |
| GuidetoPHARMACOLOGY ID | 1305 |
| PharmGKB ID | PA33139 |
| KEGG ID | hsa:5150 |
| DIP ID | |
| STRING ID | 9606.ENSP00000385632 |
| IntAct ID | Q13946 |
| DMDM | 3182958 |
| BRENDA | 3.1.4.53 |
| Reactome | R-HSA-418555 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 5150 |
| BindingDB | Q13946 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.909 | 0.003 | 0.983 | 0.004 | 0.946 | 0.005 | 0.945 | 0.005 | 0.980 | 0.000 | 0.895 | 0.005 | Download |
| Estate fingerprints | 0.752 | 0.004 | 0.746 | 0.006 | 0.749 | 0.006 | 0.749 | 0.006 | 0.863 | 0.005 | 0.497 | 0.011 | Download |
| MACCS fingerprints | 0.903 | 0.005 | 0.815 | 0.007 | 0.859 | 0.003 | 0.863 | 0.005 | 0.920 | 0.000 | 0.716 | 0.008 | Download |
| Daylight fingerprints | 0.922 | 0.004 | 0.862 | 0.006 | 0.892 | 0.004 | 0.894 | 0.005 | 0.920 | 0.000 | 0.783 | 0.007 | Download |
| ECFP2 fingerprints | 0.936 | 0.005 | 0.944 | 0.004 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.878 | 0.004 | Download |
| ECFP4 fingerprints | 0.937 | 0.005 | 0.981 | 0.005 | 0.959 | 0.003 | 0.959 | 0.003 | 0.990 | 0.000 | 0.921 | 0.006 | Download |
| ECFP6 fingerprints | 0.922 | 0.008 | 1.000 | 0.000 | 0.961 | 0.006 | 0.957 | 0.005 | 0.990 | 0.000 | 0.922 | 0.006 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: jiedong@csu.edu.cn
 |
 |
 |
 |
 |
 |