Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). TUBB2B is implicated in neuronal migration.
| Uniprot primary ID | Q3KRE8 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 253414 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | rno:291081 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000023582 |
| IntAct ID | Q3KRE8 |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-2467813 R-RNO-5626467 R-RNO-389960 R-RNO-389977 R-RNO-190840 R-RNO-68877 R-RNO-380320 R-RNO-983189 R-RNO-1445148 R-RNO-2132295 R-RNO-5663220 R-RNO-5617833 R-RNO-5620924 R-RNO-2500257 R-RNO-5632684 R-RNO-5610787 R-RNO-437239 R-RNO-389957 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 291081 |
| BindingDB | Q3KRE8 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.968 | 0.004 | 0.948 | 0.005 | 0.958 | 0.004 | 0.958 | 0.004 | 0.990 | 0.000 | 0.914 | 0.007 | Download |
| Estate fingerprints | 0.848 | 0.008 | 0.828 | 0.009 | 0.838 | 0.008 | 0.838 | 0.008 | 0.931 | 0.003 | 0.673 | 0.014 | Download |
| MACCS fingerprints | 0.969 | 0.003 | 0.889 | 0.000 | 0.929 | 0.003 | 0.930 | 0.000 | 0.970 | 0.000 | 0.859 | 0.003 | Download |
| Daylight fingerprints | 0.901 | 0.010 | 0.905 | 0.012 | 0.903 | 0.007 | 0.902 | 0.006 | 0.959 | 0.003 | 0.805 | 0.014 | Download |
| ECFP2 fingerprints | 0.988 | 0.004 | 0.928 | 0.006 | 0.958 | 0.004 | 0.958 | 0.004 | 0.990 | 0.000 | 0.919 | 0.009 | Download |
| ECFP4 fingerprints | 0.990 | 0.000 | 0.970 | 0.005 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.957 | 0.007 | Download |
| ECFP6 fingerprints | 0.990 | 0.000 | 0.986 | 0.003 | 0.988 | 0.004 | 0.988 | 0.004 | 1.000 | 0.000 | 0.969 | 0.003 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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