Target name

Q3KRE8: Tubulin beta-2B chain


  Protein function

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). TUBB2B is implicated in neuronal migration.

  Database links

Uniprot primary ID Q3KRE8
PDB ID
DrugBank ID
BioGrid ID 253414
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID rno:291081
DIP ID
STRING ID 10116.ENSRNOP00000023582
IntAct ID Q3KRE8
DMDM
BRENDA
Reactome R-RNO-2467813 R-RNO-5626467 R-RNO-389960 R-RNO-389977 R-RNO-190840 R-RNO-68877 R-RNO-380320 R-RNO-983189 R-RNO-1445148 R-RNO-2132295 R-RNO-5663220 R-RNO-5617833 R-RNO-5620924 R-RNO-2500257 R-RNO-5632684 R-RNO-5610787 R-RNO-437239 R-RNO-389957
SignaLink
BioCyc
Entrez Gene (Gene ID) 291081
BindingDB Q3KRE8

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.968 0.004 0.948 0.005 0.958 0.004 0.958 0.004 0.990 0.000 0.914 0.007 Download
Estate fingerprints 0.848 0.008 0.828 0.009 0.838 0.008 0.838 0.008 0.931 0.003 0.673 0.014 Download
MACCS fingerprints 0.969 0.003 0.889 0.000 0.929 0.003 0.930 0.000 0.970 0.000 0.859 0.003 Download
Daylight fingerprints 0.901 0.010 0.905 0.012 0.903 0.007 0.902 0.006 0.959 0.003 0.805 0.014 Download
ECFP2 fingerprints 0.988 0.004 0.928 0.006 0.958 0.004 0.958 0.004 0.990 0.000 0.919 0.009 Download
ECFP4 fingerprints 0.990 0.000 0.970 0.005 0.980 0.000 0.980 0.000 1.000 0.000 0.957 0.007 Download
ECFP6 fingerprints 0.990 0.000 0.986 0.003 0.988 0.004 0.988 0.004 1.000 0.000 0.969 0.003 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn