Target name

Q95136: D(1A) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID Q95136
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:281125
DIP ID
STRING ID 9913.ENSBTAP00000054107
IntAct ID
DMDM
BRENDA
Reactome R-BTA-418555 R-BTA-390651
SignaLink
BioCyc
Entrez Gene (Gene ID) 281125
BindingDB Q95136

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.912 0.010 0.868 0.009 0.890 0.008 0.893 0.008 0.953 0.005 0.783 0.016 Download
Estate fingerprints 0.765 0.005 0.853 0.005 0.809 0.003 0.802 0.006 0.914 0.005 0.622 0.006 Download
MACCS fingerprints 0.888 0.008 0.808 0.005 0.848 0.004 0.855 0.005 0.923 0.005 0.699 0.007 Download
Daylight fingerprints 0.800 0.014 0.770 0.004 0.785 0.005 0.788 0.009 0.818 0.004 0.569 0.013 Download
ECFP2 fingerprints 0.959 0.006 0.875 0.009 0.917 0.007 0.922 0.006 0.970 0.000 0.839 0.012 Download
ECFP4 fingerprints 0.953 0.009 0.899 0.005 0.926 0.005 0.926 0.005 0.980 0.000 0.848 0.010 Download
ECFP6 fingerprints 0.921 0.007 0.931 0.008 0.926 0.005 0.926 0.005 0.980 0.000 0.851 0.006 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn