Target name

Q95323: Carbonic anhydrase 4


  Protein function

Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity).

  Database links

Uniprot primary ID Q95323
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:280741
DIP ID
STRING ID 9913.ENSBTAP00000023909
IntAct ID
DMDM
BRENDA
Reactome R-BTA-1237044 R-BTA-1247673 R-BTA-1475029
SignaLink
BioCyc
Entrez Gene (Gene ID) 280741
BindingDB Q95323

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.970 0.000 0.950 0.000 0.960 0.000 0.960 0.000 0.990 0.000 0.920 0.000 Download
Estate fingerprints 0.970 0.000 0.950 0.000 0.960 0.000 0.960 0.000 0.990 0.000 0.920 0.000 Download
MACCS fingerprints 1.000 0.000 0.880 0.000 0.940 0.000 0.940 0.000 0.988 0.004 0.890 0.000 Download
Daylight fingerprints 0.819 0.003 0.821 0.000 0.820 0.000 0.820 0.000 0.880 0.000 0.639 0.003 Download
ECFP2 fingerprints 0.991 0.003 0.989 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.971 0.003 Download
ECFP4 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.970 0.000 Download
ECFP6 fingerprints 0.980 0.000 0.984 0.000 0.982 0.004 0.982 0.004 1.000 0.000 0.970 0.000 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn