Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
| Uniprot primary ID | Q99705 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 280 |
| PharmGKB ID | PA28867 |
| KEGG ID | hsa:2847 |
| DIP ID | |
| STRING ID | 9606.ENSP00000249016 |
| IntAct ID | |
| DMDM | 33860175 |
| BRENDA | |
| Reactome | R-HSA-418594 R-HSA-5620922 R-HSA-375276 R-HSA-416476 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 2847 |
| BindingDB | Q99705 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.910 | 0.000 | 0.830 | 0.000 | 0.870 | 0.000 | 0.879 | 0.003 | 0.945 | 0.005 | 0.741 | 0.003 | Download |
| Estate fingerprints | 0.830 | 0.000 | 0.726 | 0.000 | 0.778 | 0.004 | 0.790 | 0.000 | 0.850 | 0.000 | 0.555 | 0.005 | Download |
| MACCS fingerprints | 0.840 | 0.000 | 0.720 | 0.000 | 0.780 | 0.000 | 0.790 | 0.000 | 0.870 | 0.000 | 0.560 | 0.000 | Download |
| Daylight fingerprints | 0.800 | 0.000 | 0.860 | 0.000 | 0.830 | 0.000 | 0.830 | 0.000 | 0.900 | 0.000 | 0.668 | 0.004 | Download |
| ECFP2 fingerprints | 0.920 | 0.000 | 0.900 | 0.000 | 0.910 | 0.000 | 0.910 | 0.000 | 0.970 | 0.000 | 0.819 | 0.003 | Download |
| ECFP4 fingerprints | 0.929 | 0.003 | 0.955 | 0.000 | 0.942 | 0.004 | 0.940 | 0.000 | 0.990 | 0.000 | 0.890 | 0.000 | Download |
| ECFP6 fingerprints | 0.899 | 0.003 | 0.975 | 0.000 | 0.937 | 0.005 | 0.930 | 0.000 | 0.990 | 0.000 | 0.873 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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