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The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
| Uniprot primary ID | Q9H3N8 |
| PDB ID | |
| DrugBank ID | DB06148 DB01142 DB00667 DB00477 DB00334 DB00321 DB00408 |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 265 |
| PharmGKB ID | PA134982275 |
| KEGG ID | hsa:59340 |
| DIP ID | |
| STRING ID | 9606.ENSP00000256906 |
| IntAct ID | |
| DMDM | 14194819 |
| BRENDA | |
| Reactome | R-HSA-418594 R-HSA-390650 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 59340 |
| BindingDB | Q9H3N8 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.910 | 0.000 | 0.950 | 0.003 | 0.930 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.858 | 0.004 | Download |
| Estate fingerprints | 0.915 | 0.005 | 0.883 | 0.005 | 0.899 | 0.003 | 0.900 | 0.000 | 0.950 | 0.000 | 0.794 | 0.005 | Download |
| MACCS fingerprints | 0.919 | 0.003 | 0.879 | 0.004 | 0.899 | 0.003 | 0.900 | 0.000 | 0.960 | 0.000 | 0.792 | 0.004 | Download |
| Daylight fingerprints | 0.855 | 0.005 | 0.837 | 0.000 | 0.846 | 0.005 | 0.849 | 0.003 | 0.890 | 0.000 | 0.690 | 0.000 | Download |
| ECFP2 fingerprints | 0.958 | 0.004 | 0.942 | 0.005 | 0.950 | 0.000 | 0.952 | 0.004 | 0.990 | 0.000 | 0.904 | 0.005 | Download |
| ECFP4 fingerprints | 0.958 | 0.004 | 0.982 | 0.005 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.931 | 0.003 | Download |
| ECFP6 fingerprints | 0.950 | 0.000 | 0.990 | 0.005 | 0.970 | 0.000 | 0.968 | 0.004 | 0.990 | 0.000 | 0.936 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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