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E-mail: biomed@csu.edu.cn
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.
| Uniprot primary ID | Q9QYJ6 |
| PDB ID | 3HR1 2OVV 2OVY 3QPP 3QPN 3QPO 3HQW 3LXG 3HQZ 3HQY 2O8H |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | rno:63885 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000060834 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-418457 R-RNO-418555 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 63885 |
| BindingDB | Q9QYJ6 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.980 | 0.000 | 0.974 | 0.005 | 0.977 | 0.005 | 0.977 | 0.005 | 0.990 | 0.000 | 0.952 | 0.004 | Download |
| Estate fingerprints | 0.926 | 0.005 | 0.906 | 0.000 | 0.916 | 0.005 | 0.920 | 0.000 | 0.965 | 0.005 | 0.834 | 0.005 | Download |
| MACCS fingerprints | 0.895 | 0.005 | 0.907 | 0.005 | 0.901 | 0.003 | 0.901 | 0.003 | 0.970 | 0.000 | 0.806 | 0.005 | Download |
| Daylight fingerprints | 0.858 | 0.011 | 0.990 | 0.004 | 0.924 | 0.007 | 0.921 | 0.009 | 0.990 | 0.000 | 0.858 | 0.011 | Download |
| ECFP2 fingerprints | 0.944 | 0.005 | 0.986 | 0.000 | 0.965 | 0.005 | 0.965 | 0.005 | 1.000 | 0.000 | 0.930 | 0.005 | Download |
| ECFP4 fingerprints | 0.979 | 0.003 | 1.000 | 0.000 | 0.990 | 0.000 | 0.990 | 0.000 | 1.000 | 0.000 | 0.979 | 0.003 | Download |
| ECFP6 fingerprints | 0.970 | 0.000 | 1.000 | 0.000 | 0.986 | 0.005 | 0.986 | 0.005 | 1.000 | 0.000 | 0.970 | 0.000 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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