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E-mail: biomed@csu.edu.cn
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The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist).
| Uniprot primary ID | Q9QYN8 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 264 |
| PharmGKB ID | |
| KEGG ID | rno:85268 |
| DIP ID | |
| STRING ID | |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-418594 R-RNO-390650 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 85268 |
| BindingDB | Q9QYN8 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.890 | 0.000 | 0.870 | 0.000 | 0.880 | 0.000 | 0.880 | 0.000 | 0.941 | 0.003 | 0.754 | 0.005 | Download |
| Estate fingerprints | 0.869 | 0.003 | 0.789 | 0.003 | 0.829 | 0.003 | 0.834 | 0.005 | 0.890 | 0.000 | 0.659 | 0.006 | Download |
| MACCS fingerprints | 0.912 | 0.004 | 0.808 | 0.000 | 0.860 | 0.000 | 0.862 | 0.004 | 0.930 | 0.000 | 0.719 | 0.003 | Download |
| Daylight fingerprints | 0.710 | 0.000 | 0.822 | 0.000 | 0.766 | 0.005 | 0.750 | 0.000 | 0.838 | 0.004 | 0.532 | 0.004 | Download |
| ECFP2 fingerprints | 0.970 | 0.000 | 0.950 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.922 | 0.004 | Download |
| ECFP4 fingerprints | 0.969 | 0.003 | 0.971 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.949 | 0.003 | Download |
| ECFP6 fingerprints | 0.953 | 0.005 | 0.987 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.945 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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