Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis (By similarity).
| Uniprot primary ID | Q9QZN9 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 57 |
| PharmGKB ID | |
| KEGG ID | rno:57302 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000012342 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-418594 R-RNO-373076 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 57302 |
| BindingDB | Q9QZN9 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.856 | 0.013 | 0.962 | 0.005 | 0.909 | 0.009 | 0.906 | 0.008 | 0.950 | 0.000 | 0.826 | 0.014 | Download |
| Estate fingerprints | 0.820 | 0.009 | 0.786 | 0.013 | 0.803 | 0.009 | 0.808 | 0.009 | 0.890 | 0.000 | 0.610 | 0.016 | Download |
| MACCS fingerprints | 0.893 | 0.015 | 0.873 | 0.010 | 0.883 | 0.007 | 0.884 | 0.010 | 0.946 | 0.005 | 0.767 | 0.016 | Download |
| Daylight fingerprints | 0.769 | 0.010 | 0.927 | 0.008 | 0.848 | 0.006 | 0.833 | 0.007 | 0.855 | 0.005 | 0.701 | 0.012 | Download |
| ECFP2 fingerprints | 0.931 | 0.010 | 0.959 | 0.007 | 0.945 | 0.007 | 0.945 | 0.007 | 0.980 | 0.000 | 0.890 | 0.014 | Download |
| ECFP4 fingerprints | 0.932 | 0.004 | 0.968 | 0.003 | 0.950 | 0.000 | 0.950 | 0.000 | 0.980 | 0.000 | 0.902 | 0.004 | Download |
| ECFP6 fingerprints | 0.912 | 0.004 | 0.976 | 0.005 | 0.944 | 0.005 | 0.944 | 0.005 | 0.980 | 0.000 | 0.892 | 0.008 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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