Target name

Q9QZN9: Cannabinoid receptor 2


  Protein function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis (By similarity).

  Database links

Uniprot primary ID Q9QZN9
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 57
PharmGKB ID
KEGG ID rno:57302
DIP ID
STRING ID 10116.ENSRNOP00000012342
IntAct ID
DMDM
BRENDA
Reactome R-RNO-418594 R-RNO-373076
SignaLink
BioCyc
Entrez Gene (Gene ID) 57302
BindingDB Q9QZN9

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.856 0.013 0.962 0.005 0.909 0.009 0.906 0.008 0.950 0.000 0.826 0.014 Download
Estate fingerprints 0.820 0.009 0.786 0.013 0.803 0.009 0.808 0.009 0.890 0.000 0.610 0.016 Download
MACCS fingerprints 0.893 0.015 0.873 0.010 0.883 0.007 0.884 0.010 0.946 0.005 0.767 0.016 Download
Daylight fingerprints 0.769 0.010 0.927 0.008 0.848 0.006 0.833 0.007 0.855 0.005 0.701 0.012 Download
ECFP2 fingerprints 0.931 0.010 0.959 0.007 0.945 0.007 0.945 0.007 0.980 0.000 0.890 0.014 Download
ECFP4 fingerprints 0.932 0.004 0.968 0.003 0.950 0.000 0.950 0.000 0.980 0.000 0.902 0.004 Download
ECFP6 fingerprints 0.912 0.004 0.976 0.005 0.944 0.005 0.944 0.005 0.980 0.000 0.892 0.008 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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