Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
Uniprot primary ID | O43614 |
PDB ID | 4S0V |
DrugBank ID | DB09034 |
BioGrid ID | |
GuidetoPHARMACOLOGY ID | 322 |
PharmGKB ID | PA29223 |
KEGG ID | hsa:3062 |
DIP ID | |
STRING ID | 9606.ENSP00000359899 |
IntAct ID | |
DMDM | |
BRENDA | |
Reactome | R-HSA-389397 R-HSA-416476 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 3062 |
BindingDB | O43614 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.898 | 0.008 | 0.932 | 0.004 | 0.915 | 0.007 | 0.913 | 0.007 | 0.970 | 0.000 | 0.830 | 0.009 | Download |
Estate fingerprints | 0.886 | 0.007 | 0.758 | 0.005 | 0.822 | 0.004 | 0.834 | 0.005 | 0.890 | 0.000 | 0.651 | 0.009 | Download |
MACCS fingerprints | 0.857 | 0.005 | 0.775 | 0.005 | 0.816 | 0.005 | 0.823 | 0.005 | 0.910 | 0.000 | 0.636 | 0.008 | Download |
Daylight fingerprints | 0.849 | 0.006 | 0.855 | 0.003 | 0.852 | 0.004 | 0.852 | 0.004 | 0.897 | 0.005 | 0.704 | 0.007 | Download |
ECFP2 fingerprints | 0.933 | 0.007 | 0.963 | 0.004 | 0.948 | 0.004 | 0.946 | 0.005 | 0.990 | 0.000 | 0.893 | 0.005 | Download |
ECFP4 fingerprints | 0.945 | 0.005 | 0.995 | 0.000 | 0.970 | 0.000 | 0.968 | 0.004 | 0.999 | 0.003 | 0.939 | 0.006 | Download |
ECFP6 fingerprints | 0.896 | 0.005 | 0.996 | 0.000 | 0.946 | 0.005 | 0.943 | 0.005 | 1.000 | 0.000 | 0.896 | 0.005 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn